More than 40% of people worldwide suffer from allergy and less than 50% are being treated for their symptoms.
Allergic reactions are caused by an overreaction of the immune system to substances, called allergens, that are harmless for most people. People can develop allergies to specific food (e.g. peanut, milk, fish), grass- or tree pollen, house dust mites, pets, insects, and even some medication.
An allergic reaction may cause a wide range of symptoms. In the most severe cases it can even lead to asthmatic attacks, anaphylactic shock and even death. Although allergies are sometimes mistakenly seen as a “trivial” disease, statistics show that in fact they are seriously debilitating and severely impact the quality of life of patients.
50% of schoolchildren in Europe suffer from one or more allergies, making allergy becoming a true epidemic.
Current immunotherapy is based on desensitization and can take up to 3-5 years ( 60 injections) to reduce allergy symptoms with the risk of severe adverse reactions.
Food allergies are an increasing medical concern, as 8% of children suffer from food allergies, from which 38.7% have a history of serious reactions requiring hospitalization.
Allergy is a common condition seen in animals.
In dogs, the most common symptom associated with allergies is itchy skin (ears and their paws) or may affect the digestive system, resulting in vomiting and diarrhea.
Environmental allergens, such as house dust mite or pollen, can cause an atopic allergic reactions or atopic dermatitis with the risk of secondary infection.
By far the most prevalent equine allergy is hypersensitivity to the saliva from insect bites. The most severe form of this allergy is sweet itch, a reaction to tiny biting midges (Culicoides spp.)
At GlycoTreat’s Allergen ImmunoTherapy can be applied to a broad range of allergens responsible for veterinary allergies.
Peanut allergy is the most common food allergy in children and is usually lifelong.
When a child with a peanut allergy is exposed to peanut it triggers an immune reaction leading to anaphylaxis – a life-threatening whole-body response resulting in impaired breathing, swelling in the throat, a sudden drop in blood pressure, pale skin or blue lips, fainting and dizziness.
There is no cure for peanut allergy. The only treatment available consists of controlled exposure to small amounts of peanut protein every day, decreasing sensitivity to reduce the severity of the allergic reaction.
GlycoTreat is working to develop an ImmunoTherapy that will retrain the immune system that peanuts are safe, to provide a lifelong cure for peanut allergies.
House Dust Mite allergy is one of the most common allergies, affecting more than 500 million people worldwide, caused by an allergic reaction to the droppings of dust mites. House dust mite allergens can cause persistent rhinitis and respiratory or dermatological allergic conditions including asthma and eczema.
Patients with HDM allergy often suffer from multiple allergies (poly allergy), with a severe impact on tiredness, sleep and school performance or professional activities.
GlycoTreat’s Allergen ImmunoTherapy changes the way allergies are treated by inducing tolerance towards HDM in a short term treatment, improving patient’s overall health and quality of life.
Pollen allergy starts with the sensitization to grass pollen. An initial allergic reaction occurs when a child is re-exposed to pollen. If the allergic reaction gets stronger over time, the child may eventually develop allergic asthma.
Current treatment are focused on desensitization, exposing a patient to increasing amounts of pollen over a period of 3 to 4 years, which is a long and burdensome process.
GlycoTreat’s Allergen ImmunoTherapy changes the way allergies are treated by inducing tolerance towards pollen in a short term treatment, preventing allergic asthma.
GlycoTreat BV.
Koningin Beatrixplantsoen 28
3818 ZB Amersfoort
The Netherlands